TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage–Related Neutrophilic Inflammation in Asthma

TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage–Related Neutrophilic Inflammation in Asthma

PurposeAlthough recent studies have highlighted the link of TIPE2 and asthma airway inflammation, its roles and molecular mechanisms in different asthma inflammatory phenotypes remain largely unknown. We evaluated sputum TIPE2 expression level and its correlation with different asthma phenotypes. Ad...

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Bibliographic Details
Main Authors: Bingqing Shi, Yuqiu Hao, Wei Li, Hongna Dong, Mengting Xu, Peng Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
asthma
phenotype
inflammation
macrophages
TIPE2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.883885/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.883885/full

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