Cascade Immune Mechanisms of Protection against Mycobacterium tuberculosis (IMPAc-TB): study protocol for the Household Contact Study in the Western Cape, South Africa

Cascade Immune Mechanisms of Protection against Mycobacterium tuberculosis (IMPAc-TB): study protocol for the Household Contact Study in the Western Cape, South Africa

Abstract Background Natural immunity against Mycobacterium tuberculosis exists, and > 90% of those infected remain disease-free. Innate and adaptive immune responses required to mediate such protection against tuberculosis (TB) are, however, poorly understood. Methods This is an analytical study...

Full description

Bibliographic Details
Main Authors: Andriёtte M. Hiemstra, Candice E. MacDonald, Ilana C. van Rensburg, Kim Stanley, Elizna Maasdorp, Shirley Mc Anda, Susanne Tönsing, Jane Alexandra Shaw, Gerard Tromp, Gian D. van der Spuy, Kevin B. Urdahl, David M. Lewinsohn, Helena Kuivaniemi, Nelita Du Plessis, Stephanus T. Malherbe, Gerhard Walzl
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
Immune response
Bronchoalveolar lavage
PET-CT imaging
Household contacts
SARS-CoV-2
Online Access:https://doi.org/10.1186/s12879-022-07349-8

Internet

https://doi.org/10.1186/s12879-022-07349-8

Similar Items