Excess Branched-Chain Amino Acids Suppress Mitochondrial Function and Biogenic Signaling but Not Mitochondrial Dynamics in a Myotube Model of Skeletal Muscle Insulin Resistance

Branched-chain amino acids (BCAA) are correlated with severity of insulin resistance, which may partially result from mitochondrial dysfunction. Mitochondrial dysfunction is also common during insulin resistance and is regulated in part by altered mitochondrial fusion and fission (mitochondrial dyna...

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Bibliographic Details
Main Authors: Lindsey R. VanDerStad, Emily C. Wyatt, Roger A. Vaughan
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/14/7/389