WTD Attenuating Rheumatoid Arthritis via Suppressing Angiogenesis and Modulating the PI3K/AKT/mTOR/HIF-1α Pathway

WTD Attenuating Rheumatoid Arthritis via Suppressing Angiogenesis and Modulating the PI3K/AKT/mTOR/HIF-1α Pathway

Background: Wutou Decoction (WTD), as a classic prescription, has been generally used to treat rheumatoid arthritis (RA) for two thousand years in China. However, the potential protective effects of WTD on rheumatoid arthritis and its possible mechanism have rarely been reported.Purpose: The aim of...

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Bibliographic Details
Main Authors: Xin Ba, Ying Huang, Pan Shen, Yao Huang, Hui Wang, Liang Han, Wei Ji Lin, Hui Jia Yan, Li Jun Xu, Kai Qin, Zhe Chen, Sheng Hao Tu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
fibroblast-like synoviocytes
wutou decoction
angiogenesis
collagen-induced arthritis
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.696802/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.696802/full

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