3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells

3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic change...

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Bibliographic Details
Main Authors: Raquel González-Novo, Ana de Lope-Planelles, María Pilar Cruz Rodríguez, África González-Murillo, Elena Madrazo, David Acitores, Mario García de Lacoba, Manuel Ramírez, Javier Redondo-Muñoz
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:European Journal of Cell Biology
Subjects:
Cell migration
Epigenetics
Nuclear deformability
Acute lymphoblastic leukemia
Cell invasion
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000584

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http://www.sciencedirect.com/science/article/pii/S0171933523000584

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