Efficient reprogramming of naïve-like induced pluripotent stem cells from porcine adipose-derived stem cells with a feeder-independent and serum-free system.

Induced pluripotent stem cells (iPSCs) are somatic cells reprogrammed by ectopic expression of transcription factors or small molecule treatment, which resemble embryonic stem cells (ESCs). They hold great promise for improving the generation of genetically modified large animals. However, few porci...

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Bibliographic Details
Main Authors: Yu Zhang, Chao Wei, Pengfei Zhang, Xia Li, Tong Liu, Yong Pu, Yunsheng Li, Zubing Cao, Hongguo Cao, Ya Liu, Xiaorong Zhang, Yunhai Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3896366?pdf=render