The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes

The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes

Focal segmental glomerulosclerosis (FSGS) is a major cause of end-stage renal disease and remains without specific treatment. To identify new events during FSGS progression, we used an experimental model of FSGS associated with nephroangiosclerosis in rats injected with L-NAME (N<sub>ω</sub...

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Bibliographic Details
Main Authors: Virgilia Sahiri, Jonathan Caron, Elena Roger, Christophe Desterke, Khalil Ghachem, Inna Mohamadou, Justine Serre, Niki Prakoura, Soraya Fellahi, Sandrine Placier, Sahil Adriouch, Lu Zhang, Christos E. Chadjichristos, Christos Chatziantoniou, Hans Kristian Lorenzo, Jean-Jacques Boffa
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
glomerular diseases
proteinuria
chronic kidney disease progression
FSGS
podocytes
apoptosis
Online Access:https://www.mdpi.com/1422-0067/24/3/2723

Internet

https://www.mdpi.com/1422-0067/24/3/2723

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