Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika virus microcephaly

Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika virus microcephaly

Summary: Characterizing perturbation of molecular pathways in congenital Zika virus (ZIKV) infection is critical for improved therapeutic approaches. Leveraging integrative systems biology, proteomics, and RNA-seq, we analyzed embryonic brain tissues from an immunocompetent, wild-type congenital ZIK...

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Bibliographic Details
Main Authors: Kimino Fujimura, Amanda J. Guise, Tojo Nakayama, Christoph N. Schlaffner, Anais Meziani, Mukesh Kumar, Long Cheng, Dylan J. Vaughan, Andrew Kodani, Simon Van Haren, Kenneth Parker, Ofer Levy, Ann F. Durbin, Irene Bosch, Lee Gehrke, Hanno Steen, Ganeshwaran H. Mochida, Judith A. Steen
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Immunology
Virology
Developmental neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223009860

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http://www.sciencedirect.com/science/article/pii/S2589004223009860

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