Leukocyte Activation Profile Assessed by Raman Spectroscopy Helps Diagnosing Infection and Sepsis

Objectives:. Leukocytes are first responders to infection. Their activation state can reveal information about specific host immune response and identify dysregulation in sepsis. This study aims to use the Raman spectroscopic fingerprints of blood-derived leukocytes to differentiate inflammation, in...

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Bibliographic Details
Main Authors: Anuradha Ramoji, PhD, Daniel Thomas-Rüddel, MD, Oleg Ryabchykov, PhD, Michael Bauer, MD, Natalie Arend, MSc, Evangelos J. Giamarellos-Bourboulis, MD, Jesper Eugen-Olsen, PhD, Michael Kiehntopf, MD, Thomas Bocklitz, PhD, Jürgen Popp, PhD, Frank Bloos, MD, PhD, Ute Neugebauer, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2021-05-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000394