A novel DNA damage repair-related gene signature predicting survival, immune infiltration and drug sensitivity in cervical cancer based on single cell sequencing

A novel DNA damage repair-related gene signature predicting survival, immune infiltration and drug sensitivity in cervical cancer based on single cell sequencing

BackgroundAberrant DNA damage repair (DDR) is one of the hallmarks of tumors, and therapeutic approaches targeting this feature are gaining increasing attention. This study aims to develop a signature of DDR-related genes to evaluate the prognosis of cervical cancer (CC).MethodsDifferentially expres...

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Bibliographic Details
Main Authors: Xiaoqing Xiang, Jiawen Kang, Jingwen Jiang, Yaning Zhang, Yong Zhang, Lesai Li, Xiaoning Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
cervical cancer
DNA damage repair
prognostic signature
bulk sequencing
single-cell RNA sequencing analysis
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1198391/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1198391/full

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