Anthrax protective antigen is a calcium-dependent serine protease

Anthrax protective antigen is a calcium-dependent serine protease

Bacillus anthracis secretes a three component exotoxin-complex, which contributes to anthrax pathogenesis. Formation of this complex starts with the binding of protective antigen (PA) to its cellular receptor. In this study, we report that PA is a calcium-dependent serine protease and that the prote...

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Bibliographic Details
Main Authors: Lisanne Storm, Floris J. Bikker, Kamran Nazmi, Albert G. Hulst, Debora V. der Riet-Van Oeveren, Enno C.I. Veerman, John P. Hays, Wendy E. Kaman
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Protective antigen
B. anthracis
calcium
serine protease
ANTXR1/2 receptor
Online Access:http://dx.doi.org/10.1080/21505594.2018.1486139

Internet

http://dx.doi.org/10.1080/21505594.2018.1486139

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