Synergistic Malaria Parasite Killing by Two Types of Plasmodial Surface Anion Channel Inhibitors.

Synergistic Malaria Parasite Killing by Two Types of Plasmodial Surface Anion Channel Inhibitors.

Malaria parasites increase their host erythrocyte's permeability to a broad range of ions and organic solutes. The plasmodial surface anion channel (PSAC) mediates this uptake and is an established drug target. Development of therapies targeting this channel is limited by several problems inclu...

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Bibliographic Details
Main Authors: Margaret Pain, Alexandra W Fuller, Katherine Basore, Ajay D Pillai, Tsione Solomon, Abdullah A B Bokhari, Sanjay A Desai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4750852?pdf=render

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http://europepmc.org/articles/PMC4750852?pdf=render

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