Immune Profile of Blood, Tissue and Peritoneal Fluid: A Comparative Study in High Grade Serous Epithelial Ovarian Cancer Patients at Interval Debulking Surgery

Immune Profile of Blood, Tissue and Peritoneal Fluid: A Comparative Study in High Grade Serous Epithelial Ovarian Cancer Patients at Interval Debulking Surgery

High-grade serous epithelial ovarian carcinoma (HGSOC) is an immunogenic tumor with a unique tumor microenvironment (TME) that extends to the peritoneal cavity. The immunosuppressive nature of TME imposes the major challenge to develop effective treatment options for HGSOC. Interaction of immune cel...

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Bibliographic Details
Main Authors: Pavan Kumar, Samruddhi Ranmale, Hemant Tongaonkar, Jayanti Mania-Pramanik
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Vaccines
Subjects:
ovarian cancer
tumor microenvironment
NK cell receptors
immune modulation
cognate ligands
Online Access:https://www.mdpi.com/2076-393X/10/12/2121

Internet

https://www.mdpi.com/2076-393X/10/12/2121

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