Prognostic significance of tumor infiltrating lymphocytes on first-line pembrolizumab efficacy in advanced non-small cell lung cancer

Prognostic significance of tumor infiltrating lymphocytes on first-line pembrolizumab efficacy in advanced non-small cell lung cancer

Abstract Aim Tumor-infiltrating lymphocytes (TILs) in the tumor and stroma are expected to accurately predict the efficacy of programmed death-1 (PD-1) blockade therapy. However, little is known about the prognostic significance of TILs in first-line PD-1 therapy. We assessed TILs in patients with a...

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Bibliographic Details
Main Authors: Kyoichi Kaira, Ou Yamaguchi, Tomonori Kawasaki, Kousuke Hashimoto, Yu Miura, Ayako Shiono, Atsuto Mouri, Hisao Imai, Kunihiko Kobayashi, Masanori Yasuda, Hiroshi Kagamu
Format: Article
Language:English
Published: Springer 2023-01-01
Series:Discover Oncology
Subjects:
Tumor-infiltrating lymphocytes
CD4
CD8
PD-1
PD-L1
Non-small cell lung cancer
Online Access:https://doi.org/10.1007/s12672-023-00615-4

Internet

https://doi.org/10.1007/s12672-023-00615-4

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