Expansion microscopy using a single anchor molecule for high-yield multiplexed imaging of proteins and RNAs.

Expansion microscopy using a single anchor molecule for high-yield multiplexed imaging of proteins and RNAs.

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Expansion microscopy (ExM), by physically enlarging specimens in an isotropic fashion, enables nanoimaging on standard light microscopes. Key to existing ExM protocols is the equipping of different kinds of molecules, with different kinds of anchoring moieties, so they can all be pulled apart from e...

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Bibliographic Details
Main Authors: Yi Cui, Gaojie Yang, Daniel R Goodwin, Ciara H O'Flanagan, Anubhav Sinha, Chi Zhang, Kristina E Kitko, Tay Won Shin, Demian Park, Samuel Aparicio, CRUK IMAXT Grand Challenge Consortium, Edward S Boyden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0291506

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https://doi.org/10.1371/journal.pone.0291506

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