The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.

Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segregation; however, the specific roles of most endogenous siRNAs are unclear. The h...

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Bibliographic Details
Main Authors: Sylvia E J Fischer, Taiowa A Montgomery, Chi Zhang, Noah Fahlgren, Peter C Breen, Alexia Hwang, Christopher M Sullivan, James C Carrington, Gary Ruvkun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3213143?pdf=render