Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer

Abstract Myosin 1b (Myo1b) is an important single-headed membrane-associated motor of class I myosins that participate in many critical physiological and pathological processes. Mounting evidence suggests that the dysregulation of Myo1b expression has been extensively investigated in the development...

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Bibliographic Details
Main Authors: Yi-Hong Chen, Nan-Zhu Xu, Chang Hong, Wen-Qi Li, Yi-Qiong Zhang, Xin-Yi Yu, Yue-Le Huang, Jue-Yu Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05397-1