The Effect of the Expression of the Antiapoptotic BHRF1 Gene on the Metabolic Behavior of a Hybridoma Cell Line

The Effect of the Expression of the Antiapoptotic BHRF1 Gene on the Metabolic Behavior of a Hybridoma Cell Line

One of the most important limitations of mammalian cells-based bioprocesses, and particularly hybridoma cell lines, is the accelerated metabolism related to glucose and glutamine consumption. The high uptake rates of glucose and glutamine (i.e., the main sources of carbon, nitrogen and energy) lead...

Full description

Bibliographic Details
Main Authors: Iván Martínez-Monge, Pere Comas, David Catalán-Tatjer, Jordi Prat, Antoni Casablancas, Carlos Paredes, Martí Lecina, Jordi Joan Cairó
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Applied Sciences
Subjects:
hybridoma
genome-scale metabolic model
antiapoptotic gene
mitochondrial transport
BHRF1
Online Access:https://www.mdpi.com/2076-3417/11/14/6258

Internet

https://www.mdpi.com/2076-3417/11/14/6258

Similar Items