Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Giardiasis is a common diarrheal disease caused by the protozoan parasite Giardia intestinalis. Cysteine proteases (CPs) are acknowledged as virulence factors in Giardia but their specific role in the molecular pathogenesis of disease is not known. Herein, we aimed to characterize the three main sec...

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Bibliographic Details
Main Authors: Jingyi Liu, Showgy Ma'ayeh, Dimitra Peirasmaki, Britta Lundström-Stadelmann, Lars Hellman, Staffan G. Svärd
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2018.1451284