The structure of a tetrameric septin complex reveals a hydrophobic element essential for NC-interface integrity

Abstract The septins of the yeast Saccharomyces cerevisiae assemble into hetero-octameric rods by alternating interactions between neighboring G-domains or N- and C-termini, respectively. These rods polymerize end to end into apolar filaments, forming a ring beneath the prospective new bud that expa...

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Detalhes bibliográficos
Main Authors: Benjamin Grupp, Lukas Denkhaus, Stefan Gerhardt, Matthis Vögele, Nils Johnsson, Thomas Gronemeyer
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2024-01-01
Colecção:Communications Biology
Acesso em linha:https://doi.org/10.1038/s42003-023-05734-w