The antimicrobial peptide Brevinin-2ISb enhances the innate immune response against methicillin-resistant Staphylococcus aureus by activating DAF-2/DAF-16 signaling in Caenorhabditis elegans, as determined by in vivo imaging

Abstract. Objective:. In order to study the important role and molecular mechanism of Brevinin-2 family antimicrobial peptide Brevinin-2ISb in methicillin-resistant Staphylococcus aureus (MRSA) infection of Caenorhabditis (C.) elegans, and to find the optimal therapeutic concentration of Brevinin-2I...

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Bibliographic Details
Main Authors: Hui Xie, Xu Nie, Yonghua Zhan, Qi Zeng, Xueli Chen, Dan Chen
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2020-12-01
Series:Journal of Bio-X Research
Online Access:http://journals.lww.com/10.1097/JBR.0000000000000079