Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats

Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats

Abstract Background Acute myocardial injury (AMI), which is induced by renal ischemia-reperfusion (IR), is a significant cause of acute kidney injury (AKI)-related associated death. Obesity increases the severity and frequency of AMI and AKI. Tanshinone IIA (TIIA) combined with cyclosporine A (CsA)...

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Main Authors: He Tai, Xiao-lin Jiang, Zhi-ming Lan, Yue Li, Liang Kong, Si-cheng Yao, Nan Song, Mei-jun Lv, Jin Wu, Ping Yang, Xuan-si Xiao, Guan-lin Yang, Jin-song Kuang, Lian-qun Jia
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Renal ischemia-reperfusion
Obesity
Mitochondrial dysfunction
Acute myocardial injury
Tanshinone IIA
Cyclosporine a
Online Access:https://doi.org/10.1186/s12906-021-03270-w

Internet

https://doi.org/10.1186/s12906-021-03270-w

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