Albendazole induces oxidative stress and DNA damage in the parasitic protozoan Giardia duodenalis

The control of Giardia duodenalis infections is carried out mainly by drugs, among these albendazole (ABZ) is commonly used. Although the cytotoxic effect of ABZ usually involves binding to β-tubulin, it has been suggested that oxidative stress may also play a role in its parasiticidal mechanism. In...

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Bibliographic Details
Main Authors: Rodrigo eMartínez-Espinoza, Raúl eArgüello-García, Emma eSaavedra, M. Guadalupe eOrtega-Pierres
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00800/full