Identification of Crocetin as a Dual Agonist of GPR40 and GPR120 Responsible for the Antidiabetic Effect of Saffron

Crocin, a glycoside of crocetin, has been known as the principal component responsible for saffron’s antidiabetic, anticancer, and anti-inflammatory effects. Crocetin, originating from the hydrolytic cleavage of crocin in biological systems, was subjected to ligand-based virtual screening in this in...

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Bibliographic Details
Main Authors: Xiaodi Zhao, Dohee Ahn, Gibeom Nam, Jihee Kwon, Songyi Song, Min Ji Kang, Hyejin Ahn, Sang J. Chung
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/22/4774