The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers
An ancestral inversion of 900 kb on chromosome 17q21, which includes the microtubule-associated protein tau (MAPT) gene, defines two haplotype clades in Caucasians (H1 and H2). The H1 haplotype has been linked inconsistently with AD. In a previous study, we showed that an SNP tagging this haplotype...
Główni autorzy: | , , , , , , , , , , , , , , |
---|---|
Format: | Artykuł |
Język: | English |
Wydane: |
Frontiers Media S.A.
2019-12-01
|
Seria: | Frontiers in Aging Neuroscience |
Hasła przedmiotowe: | |
Dostęp online: | https://www.frontiersin.org/article/10.3389/fnagi.2019.00327/full |