Human SERPINA3 induces neocortical folding and improves cognitive ability in mice
Abstract Neocortex expansion and folding are related to human intelligence and cognition, but the molecular and cellular mechanisms underlying cortical folding remain poorly understood. Here, we report that the human gene SERPINA3 is linked to gyrification. Specifically, the overexpression of SERPIN...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2022-11-01
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| Series: | Cell Discovery |
| Online Access: | https://doi.org/10.1038/s41421-022-00469-0 |