Bacterial butyrate mediates the anti-atherosclerotic effect of silybin

Bacterial butyrate mediates the anti-atherosclerotic effect of silybin

Silybin (SIL) is a versatile bioactive compound used for improving liver damage and lipid disorders and is also thought to be beneficial for atherosclerosis (AS). The goal of this study was to investigate the efficacy of SIL in the treatment of AS in ApoE−/−mice fed a high-fat diet and explore the m...

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Bibliographic Details
Main Authors: Hao-Ran Shen, Zhi-Yu Wang, Zhen Shen, Tong-Tong Liu, Yun-Dan Guo, Tian-Le Gao, Hui-Hui Guo, Yan-Xing Han, Jian-Dong Jiang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Silybin
Atherosclerosis
Bacterial butyrate
MCT1/4
Gut integrity
Tight junction
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223017146

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http://www.sciencedirect.com/science/article/pii/S0753332223017146

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