Targeting tau in Alzheimer’s disease: from mechanisms to clinical therapy

Targeting tau in Alzheimer’s disease: from mechanisms to clinical therapy

Alzheimer’s disease is the most prevalent neurodegenerative disease affecting older adults. Primary features of Alzheimer’s disease include extracellular aggregation of amyloid-β plaques and the accumulation of neurofibrillary tangles, formed by tau protein, in the cells. While there are amyloid-β-t...

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Bibliographic Details
Main Authors: Jinwang Ye, Huali Wan, Sihua Chen, Gong-Ping Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
acetylation; alzheimer’s disease; cognitive deficits; gliosis; mitochondria damage; neuroinflammation; phosphorylation; synaptic impairments; tau; tau immunotherapy
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1489;epage=1498;aulast=Ye

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1489;epage=1498;aulast=Ye

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