Epitope-Specific Anti-SerpinB3 Antibodies for SerpinB3 Recognition and Biological Activity Inhibition

Epitope-Specific Anti-SerpinB3 Antibodies for SerpinB3 Recognition and Biological Activity Inhibition

SerpinB3 is a serine protease inhibitor that plays a relevant role in disease progression and cancer by increasing fibrosis, cell proliferation, and invasion, besides conferring resistance to apoptosis. The mechanisms underlying these biological activities are not yet fully understood. The aim of th...

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Bibliographic Details
Main Authors: Alessandra Biasiolo, Michele Sandre, Stefania Ferro, Santina Quarta, Mariagrazia Ruvoletto, Gianmarco Villano, Cristian Turato, Maria Guido, Oriano Marin, Patrizia Pontisso
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
SerpinB3
SerpinB4
immunogenic epitopes
serine protease inhibitory activity
Online Access:https://www.mdpi.com/2218-273X/13/5/739

Internet

https://www.mdpi.com/2218-273X/13/5/739

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