Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins

Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins

DDX6 (p54/RCK) is a human RNA helicase with central roles in mRNA decay and translation repression. To help our understanding of how DDX6 performs these multiple functions, we conducted the first unbiased, large-scale study to map the DDX6-centric protein-protein interactome using immunoprecipitatio...

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Bibliographic Details
Main Authors: Rebecca Bish, Nerea Cuevas-Polo, Zhe Cheng, Dolores Hambardzumyan, Mathias Munschauer, Markus Landthaler, Christine Vogel
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Biomolecules
Subjects:
DDX6
post-transcriptional regulation
protein interactions
SUMOylation
NUFIP2
FAM195A
FAM195B
stress granules
P bodies
mRNA degradation
Online Access:http://www.mdpi.com/2218-273X/5/3/1441

Internet

http://www.mdpi.com/2218-273X/5/3/1441

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