Differences in Formation of Prepuce and Urethral Groove During Penile Development Between Guinea Pigs and Mice Are Controlled by Differential Expression of Shh, Fgf10 and Fgfr2

The penile tubular urethra forms by canalization of the urethral plate without forming an obvious urethral groove in mice, while the urethral epithelium forms a fully open urethral groove before urethra closure through the distal-opening-proximal-closing process in humans and guinea pigs. Our knowle...

Full description

Bibliographic Details
Main Authors: Shanshan Wang, Zhengui Zheng
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/5/348