Effect of denosumab on glucose metabolism in postmenopausal osteoporotic women with prediabetes: a study protocol for a 12-month multicenter, open-label, randomized controlled trial

Effect of denosumab on glucose metabolism in postmenopausal osteoporotic women with prediabetes: a study protocol for a 12-month multicenter, open-label, randomized controlled trial

Abstract Background Participants with prediabetes are at a high risk of developing type 2 diabetes (T2D). Recent studies have suggested that blocking the receptor activator of nuclear factor-κB ligand (RANKL) may improve glucose metabolism and delay the development of T2D. However, the effect of den...

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Bibliographic Details
Main Authors: Yilin Wang, Yu Jiang, Jia Li, Xisheng Lin, Yan Luo, Shuhuai Tan, Haohan Yang, Zefu Gao, Xiang Cui, Pengbin Yin, Dan Kong, Yuan Gao, Yu Cheng, Licheng Zhang, Peifu Tang, Houchen Lyu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Trials
Subjects:
Denosumab
Glucose metabolism
Osteoporosis
Postmenopausal women
Prediabetes
RANKL
Online Access:https://doi.org/10.1186/s13063-023-07769-0

Internet

https://doi.org/10.1186/s13063-023-07769-0

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