Pongol Methyl Ether Inhibits Akt and Suppresses Cancer Stem Cell Phenotypes in Lung Cancer Cells

Pongol Methyl Ether Inhibits Akt and Suppresses Cancer Stem Cell Phenotypes in Lung Cancer Cells

Cancer stem cells (CSCs) are an important therapeutic target. The therapeutic agents targeting CSCs should lead to improved clinical outcomes. Here we have demonstrated the CSC-suppressing activity of pongol methyl ether (PME), a pure compound from <i>Millettia erythrocalyx</i>. Methods:...

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Bibliographic Details
Main Authors: Arnon Silapech, Satapat Racha, Nithikoon Aksorn, Pennapa Lafauy, Sucharat Tungsukruthai, Chanida Vinayanuwattikun, Boonchoo Sritularak, Pithi Chanvorachote
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceuticals
Subjects:
pongol methyl ether
cancer stem cell
lung cancer
Akt
CSC-targeting
Online Access:https://www.mdpi.com/1424-8247/14/11/1085

Internet

https://www.mdpi.com/1424-8247/14/11/1085

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