Impaired autophagy activity-induced abnormal differentiation of bone marrow stem cells is related to adolescent idiopathic scoliosis osteopenia

Impaired autophagy activity-induced abnormal differentiation of bone marrow stem cells is related to adolescent idiopathic scoliosis osteopenia

Abstract. Background:. Osteopenia has been well documented in adolescent idiopathic scoliosis (AIS). Bone marrow stem cells (BMSCs) are a crucial regulator of bone homeostasis. Our previous study revealed a decreased osteogenic ability of BMSCs in AIS-related osteopenia, but the underlying mechanism...

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Bibliographic Details
Main Authors: Hongqi Zhang, Guanteng Yang, Jiong Li, Lige Xiao, Chaofeng Guo, Yuxiang Wang, Lishao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2023-09-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002165

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http://journals.lww.com/10.1097/CM9.0000000000002165

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