UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion

Background Icaritin (ICT) has been previously demonstrated to display protective effects against cerebral ischemic reperfusion (I/R) by inhibiting oxidative stress, but the mechanism remains unclear. This study aimed to explore the mechanism from the perspective of metabolomics. Methods A mice cereb...

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Bibliographic Details
Main Authors: Yunfeng Tang, Lixin Sun, Yun Zhao, Jingchun Yao, Zhong Feng, Zhong Liu, Guimin Zhang, Chenghong Sun
Format: Article
Language:English
Published: PeerJ Inc. 2023-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14483.pdf