Enhanced protein secretion in reduced genome strains of Streptomyces lividans

Enhanced protein secretion in reduced genome strains of Streptomyces lividans

Abstract Background S. lividans TK24 is a popular host for the production of small molecules and the secretion of heterologous protein. Within its large genome, twenty-nine non-essential clusters direct the biosynthesis of secondary metabolites. We had previously constructed ten chassis strains, car...

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Bibliographic Details
Main Authors: Mohamed Belal Hamed, Tobias Busche, Kenneth Simoens, Sebastien Carpentier, Jan Kormanec, Lieve Van Mellaert, Jozef Anné, Joern Kalinowski, Kristel Bernaerts, Spyridoula Karamanou, Anastassios Economou
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Microbial Cell Factories
Subjects:
Reduced genome strains
Secretome
Proteomics
Transcriptomics
Heterologous secretion
Online Access:https://doi.org/10.1186/s12934-023-02269-x

Internet

https://doi.org/10.1186/s12934-023-02269-x

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