Enhanced protein secretion in reduced genome strains of Streptomyces lividans
Abstract Background S. lividans TK24 is a popular host for the production of small molecules and the secretion of heterologous protein. Within its large genome, twenty-nine non-essential clusters direct the biosynthesis of secondary metabolites. We had previously constructed ten chassis strains, car...
Main Authors: | Mohamed Belal Hamed, Tobias Busche, Kenneth Simoens, Sebastien Carpentier, Jan Kormanec, Lieve Van Mellaert, Jozef Anné, Joern Kalinowski, Kristel Bernaerts, Spyridoula Karamanou, Anastassios Economou |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
|
Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12934-023-02269-x |
Similar Items
-
Comprehensive subcellular topologies of polypeptides in Streptomyces
by: Konstantinos C. Tsolis, et al.
Published: (2018-03-01) -
Evaluation of Sample Preparation Methods for Inter-Laboratory Metabolomics Investigation of <i>Streptomyces lividans</i> TK24
by: Howbeer Muhamadali, et al.
Published: (2020-09-01) -
Engineered Streptomyces lividans Strains for Optimal Identification and Expression of Cryptic Biosynthetic Gene Clusters
by: Qinying Peng, et al.
Published: (2018-12-01) -
A Reporter System for Fast Quantitative Monitoring of Type 3 Protein Secretion in Enteropathogenic <i>E. coli</i>
by: Luit Barkalita, et al.
Published: (2020-11-01) -
Secretion-Based Modes of Action of Biocontrol Agents with a Focus on <i>Pseudozyma aphidis</i>
by: Dhruv Aditya Srivastava, et al.
Published: (2021-01-01)