The cis-regulatory effects of modern human-specific variants

The Neanderthal and Denisovan genomes enabled the discovery of sequences that differ between modern and archaic humans, the majority of which are noncoding. However, our understanding of the regulatory consequences of these differences remains limited, in part due to the decay of regulatory marks in...

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Bibliographic Details
Main Authors: Carly V Weiss, Lana Harshman, Fumitaka Inoue, Hunter B Fraser, Dmitri A Petrov, Nadav Ahituv, David Gokhman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63713