Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors

Synthesis of novel 7,7-difluoroprostacyclin and 15-deoxy-15,15-difluoro-PGF2? derivatives will be presented. These compounds show high affinity to prostaglandin receptors and potent biological activities.

Bibliographic Details
Main Authors: Yasushi Matsumuraa, Takashi Nakanob, Nobuaki Moria, Yoshitomi Morizawab
Format: Article
Language:deu
Published: Swiss Chemical Society 2004-03-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/3821