Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors
Synthesis of novel 7,7-difluoroprostacyclin and 15-deoxy-15,15-difluoro-PGF2? derivatives will be presented. These compounds show high affinity to prostaglandin receptors and potent biological activities.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
2004-03-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://chimia.ch/chimia/article/view/3821 |
| _version_ | 1797987734081503232 |
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| author | Yasushi Matsumuraa Takashi Nakanob Nobuaki Moria Yoshitomi Morizawab |
| author_facet | Yasushi Matsumuraa Takashi Nakanob Nobuaki Moria Yoshitomi Morizawab |
| author_sort | Yasushi Matsumuraa |
| collection | DOAJ |
| description |
Synthesis of novel 7,7-difluoroprostacyclin and 15-deoxy-15,15-difluoro-PGF2? derivatives will be presented. These compounds show high affinity to prostaglandin receptors and potent biological activities.
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| first_indexed | 2024-04-11T07:51:26Z |
| format | Article |
| id | doaj.art-52152e4854764d4a91c34bed642e2c50 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-04-11T07:51:26Z |
| publishDate | 2004-03-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-52152e4854764d4a91c34bed642e2c502022-12-22T04:36:03ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242004-03-0158310.2533/000942904777678073Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin ReceptorsYasushi MatsumuraaTakashi NakanobNobuaki MoriaYoshitomi Morizawab Synthesis of novel 7,7-difluoroprostacyclin and 15-deoxy-15,15-difluoro-PGF2? derivatives will be presented. These compounds show high affinity to prostaglandin receptors and potent biological activities. https://chimia.ch/chimia/article/view/3821AntiplateletFluorinationGlaucomaProstaglandinReceptor |
| spellingShingle | Yasushi Matsumuraa Takashi Nakanob Nobuaki Moria Yoshitomi Morizawab Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors CHIMIA Antiplatelet Fluorination Glaucoma Prostaglandin Receptor |
| title | Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors |
| title_full | Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors |
| title_fullStr | Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors |
| title_full_unstemmed | Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors |
| title_short | Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors |
| title_sort | synthesis and biological properties of novel fluoroprostaglandin derivatives highly selective and potent agonists for prostaglandin receptors |
| topic | Antiplatelet Fluorination Glaucoma Prostaglandin Receptor |
| url | https://chimia.ch/chimia/article/view/3821 |
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