SCClone: Accurate Clustering of Tumor Single-Cell DNA Sequencing Data

SCClone: Accurate Clustering of Tumor Single-Cell DNA Sequencing Data

Single-cell DNA sequencing (scDNA-seq) enables high-resolution profiling of genetic diversity among single cells and is especially useful for deciphering the intra-tumor heterogeneity and evolutionary history of tumor. Specific technical issues such as allele dropout, false-positive errors, and doub...

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Bibliografiske detaljer
Main Authors: Zhenhua Yu , Fang Du, Lijuan Song
Format: Article
Sprog:English
Udgivet: Frontiers Media S.A. 2022-01-01
Serier:Frontiers in Genetics
Fag:
single-cell sequencing
next-generation sequencing
cancer genome
intra-tumor heterogeneity
clustering
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2022.823941/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.823941/full

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