Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation

Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation

DNMT3A participates in de novo methylation, yet its impact on the proliferation of testicular Sertoli cells remains unclear. Development-specific methylation has been proven to be associated with cellular development. Therefore, in this study, we simulated DNMT3A expression pattern during testicular...

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Bibliographic Details
Main Authors: Dong Xu, Saina Yan, Huimin Jin, Chujie Chen, Xiangwei Tang, Xu Wang, Yonghong Li, Fang Fei, Anqi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Genetics
Subjects:
DNMT3A
Sertoli cells
proliferation
RRBS
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1302351/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1302351/full

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