Non-animal models for blood–brain barrier permeability evaluation of drug-like compounds

Abstract Diseases related to the central nervous system (CNS) are major health concerns and have serious social and economic impacts. Developing new drugs for CNS-related disorders presents a major challenge as it actively involves delivering drugs into the CNS. Therefore, it is imperative to develo...

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Bibliographic Details
Main Authors: Frederic O. Dehnbostel, Vaibhav A. Dixit, Robert Preissner, Priyanka Banerjee
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-59734-9