Bisphenol-A reduces DNA methylation after metabolic activation

Abstract Bisphenol-A (BPA) is an important environmental contaminant with adverse health effects suspected to be mediated through epigenetic mechanisms. We had reported that the FLO1-dependent flocculation of transgenic yeast expressing human DNA methyltransferase (DNMT yeast) is a useful tool in ep...

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Bibliographic Details
Main Authors: Kei-ichi Sugiyama, Mawo Kinoshita, Petr Grúz, Toshio Kasamatsu, Masamitsu Honma
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Genes and Environment
Subjects:
Online Access:https://doi.org/10.1186/s41021-022-00249-y