Differential Type-I Interferon Response in Buffy Coat Transcriptome of Individuals Infected with SARS-CoV-2 Gamma and Delta Variants

Differential Type-I Interferon Response in Buffy Coat Transcriptome of Individuals Infected with SARS-CoV-2 Gamma and Delta Variants

The innate immune system is the first line of defense against pathogens such as the acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The type I-interferon (IFN) response activation during the initial steps of infection is essential to prevent viral replication and tissue damage. SARS-CoV and S...

Full description

Bibliographic Details
Main Authors: Guilherme C. da Fonseca, Liliane T. F. Cavalcante, Otávio J. Brustolini, Paula M. Luz, Debora C. Pires, Emilia M. Jalil, Eduardo M. Peixoto, Beatriz Grinsztejn, Valdilea G. Veloso, Sandro Nazer, Carlos A. M. Costa, Daniel A. M. Villela, Guilherme T. Goedert, Cleber V. B. D. Santos, Nadia C. P. Rodrigues, Fernando do Couto Motta, Marilda Mendonça Siqueira, Lara E. Coelho, Claudio J. Struchiner, Ana Tereza R. Vasconcelos
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2 variants
Delta
Gamma
innate immune system
type-I interferon response
viral evolution
Online Access:https://www.mdpi.com/1422-0067/24/17/13146

Internet

https://www.mdpi.com/1422-0067/24/17/13146

Similar Items