Observations of amyloid breakdown by proteases over time using scanning acoustic microscopy

Abstract Amyloid consists of insoluble beta-fibrillar proteins with stable structures. The Congo red staining method for histologically detecting amyloid is unsuitable for quantitatively assessing amyloid fibers. Scanning acoustic microscopy (SAM) detects the attenuation of sound (AOS) through secti...

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Bibliographic Details
Main Authors: Katsutoshi Miura, Toshihide Iwashita
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48033-4