In Vivo and In Vitro Impact of Carbohydrate Variation on Human Follicle-Stimulating Hormone Function

In Vivo and In Vitro Impact of Carbohydrate Variation on Human Follicle-Stimulating Hormone Function

Human follicle-stimulating hormone (FSH) exhibits both macro- and microheterogeneity in its carbohydrate moieties. Macroheterogeneity results in three physiologically relevant FSHβ subunit variants, two that possess a single N-linked glycan at either one of the two βL1 loop glycosylation sites or on...

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Bibliographic Details
Main Authors: George R. Bousfield, Jeffrey V. May, John S. Davis, James A. Dias, T. Rajendra Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Endocrinology
Subjects:
pituitary
N-glycosylation
follicle-stimulating hormone
bone
female Infertility
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00216/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00216/full

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