Immune checkpoints in rheumatoid arthritis: progress and promise

Immune checkpoints in rheumatoid arthritis: progress and promise

Rheumatoid arthritis (RA) is one of the most prevalent autoimmune inflammatory conditions, and while the mechanisms driving pathogenesis are yet to be completely elucidated, self-reactive T cells and immune checkpoint pathways have a clear role. In this review, we provide an overview of the importan...

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Bibliographic Details
Main Authors: Annabelle Small, Katie Lowe, Mihir D. Wechalekar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
T cells
immune checkpoints
co-stimulatory pathways
CTLA-4
PD-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285554/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285554/full

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