Causal association of genetically determined plasma metabolites with osteoarthritis: a two-sample Mendelian randomization study

Causal association of genetically determined plasma metabolites with osteoarthritis: a two-sample Mendelian randomization study

BackgroundWe aimed to elucidate the causal relationship between plasma metabolites and the vulnerability to Osteoarthritis (OA), encompassing both hip OA and knee OA.MethodsWe conducted a two-way two-sample Mendelian randomization (MR) analysis to investigate the association of 1,400 plasma metaboli...

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Bibliographic Details
Main Authors: Qingsong Fu, Xinhua Yuan, Weibin Wang, Xinyou Han, Jiakai Zhang, Junlong Wu, Yao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Medicine
Subjects:
metabolites
osteoarthritis
Mendelian randomization
causal
two-sample
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1396746/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2024.1396746/full

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