Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats

Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats

The aim of this work was to prepare and optimize a solid self-nanoemulsifying drug delivery system pre-concentrate (SSP) containing water-insoluble flurbiprofen (FL) using a novel pseudo-ternary phase diagram. The pseudo-ternary phase diagram, composed of FL as the drug and dispersion core, Kollisol...

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Bibliographic Details
Main Authors: Rae Man Kim, Dong-Jin Jang, Yu Chul Kim, Jin-Ha Yoon, Kyoung Ah Min, Han-Joo Maeng, Kwan Hyung Cho
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Pharmaceutics
Subjects:
flurbiprofen
solid self-nanoemulsifying drug delivery system
dissolution
bioavailability
Online Access:https://www.mdpi.com/1999-4923/10/4/247

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https://www.mdpi.com/1999-4923/10/4/247

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